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The Good, the Bad, and the Cell Type-Specific Roles of Hypoxia Inducible Factor-1α in Neurons and Astrocytes
Hypoxia inducible factor-1α (HIF-1α) is a key regulator of oxygen homeostasis, because it is responsible for the regulation of genes involved in glycolysis, erythropoiesis, angiogenesis, and apoptosis. In the CNS, HIF-1α is stabilized by insults associated with hypoxia and ischemia. Because its many...
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| Publicado no: | J Neurosci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6671445/ https://ncbi.nlm.nih.gov/pubmed/18287515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5323-07.2008 |
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