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Spred1 Is Required for Synaptic Plasticity and Hippocampus-Dependent Learning

Germline mutations in SPRED1, a negative regulator of Ras, have been described in a neurofibromatosis type 1 (NF1)-like syndrome (NFLS) that included learning difficulties in some affected individuals. NFLS belongs to the group of phenotypically overlapping neuro-cardio-facial-cutaneous syndromes th...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Denayer, Ellen, Ahmed, Tariq, Brems, Hilde, Van Woerden, Geeske, Borgesius, Nils Zuiderveen, Callaerts-Vegh, Zsuzsanna, Yoshimura, Akihiko, Hartmann, Dieter, Elgersma, Ype, D'Hooge, Rudi, Legius, Eric, Balschun, Detlef
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671253/
https://ncbi.nlm.nih.gov/pubmed/19118178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4698-08.2008
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