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Phosphorylation of SNAP-25 at Ser187 Mediates Enhancement of Exocytosis by a Phorbol Ester in INS-1 Cells

Activation of diacylglycerol (DAG) signaling pathways with phorbol esters dramatically enhances Ca(2+)-triggered exocytosis from both endocrine cells and neurons, however the relevant targets of DAG are controversial. A possible effector mechanism for this signaling pathway is phosphorylation of SNA...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Shu, Yilong, Liu, Xin, Yang, Yan, Takahashi, Masami, Gillis, Kevin D.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671161/
https://ncbi.nlm.nih.gov/pubmed/18171919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2352-07.2008
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