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Backpropagating Action Potentials Trigger Dendritic Release of BDNF during Spontaneous Network Activity

Brain-derived neurotrophic factor (BDNF) is a major regulator of activity-dependent synapse development and plasticity. Because BDNF is a secreted protein, it has been proposed that BDNF is released from target neurons in an activity-dependent manner. However, direct evidence for postsynaptic releas...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kuczewski, Nicola, Porcher, Christophe, Ferrand, Nadine, Fiorentino, Hervé, Pellegrino, Christophe, Kolarow, Richard, Lessmann, Volkmar, Medina, Igor, Gaiarsa, Jean-Luc
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670985/
https://ncbi.nlm.nih.gov/pubmed/18596175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1673-08.2008
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