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Phorbol Esters Modulate Spontaneous and Ca(2+)-Evoked Transmitter Release via Acting on Both Munc13 and Protein Kinase C

Diacylglycerol (DAG) and phorbol esters strongly potentiate transmitter release at synapses by activating protein kinase C (PKC) and members of the Munc13 family of presynaptic vesicle priming proteins. This PKC/Munc13 pathway has emerged as a crucial regulator of release probability during various...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Lou, Xuelin, Korogod, Natalya, Brose, Nils, Schneggenburger, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670566/
https://ncbi.nlm.nih.gov/pubmed/18701688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0550-08.2008
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