Altered Neuron Excitability and Synaptic Plasticity in the Cerebellar Granular Layer of Juvenile Prion Protein Knock-Out Mice with Impaired Motor Control

Although the role of abnormal prion protein (PrP) conformation in generating infectious brain diseases (transmissible spongiform encephalopathy) has been recognized, the function of PrP in the normal brain remains mostly unknown. In this investigation, we considered the effect of PrP gene knock-out...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Prestori, Francesca, Rossi, Paola, Bearzatto, Bertrand, Lainé, Jeanne, Necchi, Daniela, Diwakar, Shyam, Schiffmann, Serge N., Axelrad, Herbert, D'Angelo, Egidio
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670502/
https://ncbi.nlm.nih.gov/pubmed/18614678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0409-08.2008
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