Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers

BACKGROUND: Mononuclear cell infiltration of exocrine glands, production of Ro/SSA and La/SSB autoantibodies, along with oral and ocular dryness, are characteristic features of primary Sjögren’s syndrome (pSS). Non-SS sicca subjects, an underexplored group in relation to pSS, display similar sicca s...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Aqrawi, Lara A., Galtung, Hilde Kanli, Guerreiro, Eduarda M., Øvstebø, Reidun, Thiede, Bernd, Utheim, Tor Paaske, Chen, Xiangjun, Utheim, Øygunn Aass, Palm, Øyvind, Skarstein, Kathrine, Jensen, Janicke Liaaen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670195/
https://ncbi.nlm.nih.gov/pubmed/31366407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-1961-4
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