Olfactory Ensheathing Cells Grafted Into the Retina of RCS Rats Suppress Inflammation by Down-Regulating the JAK/STAT Pathway

The inflammatory microenvironment in the retina plays a vital role in the pathogenesis and progression of retinitis pigmentosa (RP). Microglial inflammatory cytokines production leads to gliosis and apoptosis of retinal neurons, and ultimately, visual loss. Cell-based therapies using grafted olfacto...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Xie, Jing, Li, Yijian, Dai, Jiaman, He, Yan, Sun, Dayu, Dai, Chao, Xu, Haiwei, Yin, Zheng Qin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670006/
https://ncbi.nlm.nih.gov/pubmed/31402855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00341
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