Ex Vivo Enteroids Recapitulate In Vivo Citrulline Production in Mice

BACKGROUND: The endogenous production of arginine relies on the synthesis of citrulline by enteral ornithine transcarbamylase (OTC). Mutations in the gene coding for this enzyme are the most frequent cause of urea cycle disorders. There is a lack of correlation between in vivo metabolic function and...

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Bibliografiske detaljer
Udgivet i:J Nutr
Main Authors: Wang, Xiaoying, Yuan, Yang, Didelija, Inka C, Mohammad, Mahmoud A, Marini, Juan C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669957/
https://ncbi.nlm.nih.gov/pubmed/30184221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jn/nxy126
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