Cognitive reserve and clinical progression in Alzheimer disease: A paradoxical relationship

OBJECTIVE: To investigate the relationship between cognitive reserve (CR) and clinical progression across the Alzheimer disease (AD) spectrum. METHODS: We selected 839 β-amyloid (Aβ)–positive participants with normal cognition (NC, n = 175), mild cognitive impairment (MCI, n = 437), or AD dementia (...

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Bibliografiset tiedot
Julkaisussa:Neurology
Päätekijät: van Loenhoud, Anna Catharina, van der Flier, Wiesje Maria, Wink, Alle Meije, Dicks, Ellen, Groot, Colin, Twisk, Jos, Barkhof, Frederik, Scheltens, Philip, Ossenkoppele, Rik
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Lippincott Williams & Wilkins 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669930/
https://ncbi.nlm.nih.gov/pubmed/31266904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000007821
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