Endosome and Golgi‐associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism

Cellular homeostasis requires the ubiquitin‐dependent degradation of membrane proteins. This was assumed to be mediated exclusively either by endoplasmic reticulum‐associated degradation (ERAD) or by endosomal sorting complexes required for transport (ESCRT)‐dependent lysosomal degradation. We ident...

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Detaylı Bibliyografya
Yayımlandı:EMBO J
Asıl Yazarlar: Schmidt, Oliver, Weyer, Yannick, Baumann, Verena, Widerin, Michael A, Eising, Sebastian, Angelova, Mihaela, Schleiffer, Alexander, Kremser, Leopold, Lindner, Herbert, Peter, Matthias, Fröhlich, Florian, Teis, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669922/
https://ncbi.nlm.nih.gov/pubmed/31368600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101433
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