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Homology Modelling and Molecular Docking Studies of Selected Substituted Benzo[d]imidazol-1-yl)methyl)benzimidamide Scaffolds on Plasmodium falciparum Adenylosuccinate Lyase Receptor

Plasmodium falciparum adenylosuccinate lyase (PfADSL) is an important enzyme in purine metabolism. Although several benzimidazole derivatives have been commercially developed into drugs, the template design as inhibitor against PfADSL has not been fully explored. This study aims to model the 3-dimen...

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Bibliographische Detailangaben
Veröffentlicht in:Bioinform Biol Insights
Hauptverfasser: Oduselu, Gbolahan O, Ajani, Olayinka O, Ajamma, Yvonne U, Brors, Benedikt, Adebiyi, Ezekiel
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669854/
https://ncbi.nlm.nih.gov/pubmed/31391779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1177932219865533
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