Genetic predisposition to increased serum calcium, bone mineral density, and fracture risk in individuals with normal calcium levels: mendelian randomisation study

OBJECTIVE: To determine if genetically increased serum calcium levels are associated with improved bone mineral density and a reduction in osteoporotic fractures. DESIGN: Mendelian randomisation study. SETTING: Cohorts used included: the UK Biobank cohort, providing genotypic and estimated bone mine...

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Detalhes bibliográficos
Publicado no:BMJ
Main Authors: Cerani, Agustin, Zhou, Sirui, Forgetta, Vincenzo, Morris, John A, Trajanoska, Katerina, Rivadeneira, Fernando, Larsson, Susanna C, Michaëlsson, Karl, Richards, J Brent
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group Ltd. 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669416/
https://ncbi.nlm.nih.gov/pubmed/31371314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmj.l4410
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