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Cochlear Pharmacokinetics - Micro-Computed Tomography and Learning-Prediction Modeling for Transport Parameter Determination

Inner ear disorders such as sensorineural deafness and genetic diseases may one day be treated with local drug delivery to the inner ear. Current pharmacokinetic models have been based on invasive methods to measure drug concentrations, limiting them in spatial resolution, and restricting the resear...

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Detalhes bibliográficos
Publicado no:Hear Res
Main Authors: Moudgalya, Sanketh S., Wilson, Kevin, Zhu, Xiaoxia, Budzevich, Mikalai M., Walton, Joseph P., Cahill, Nathan D., Frisina, Robert D., Borkholder, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669082/
https://ncbi.nlm.nih.gov/pubmed/31181459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2019.05.009
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