Association of maternal first trimester ondansetron use with cardiac malformations and oral clefts in offspring

IMPORTANCE: Evidence for the fetal safety of ondansetron, a 5-HT(3) receptor antagonist that is commonly prescribed for nausea and vomiting in pregnancy, is limited and conflicting. OBJECTIVE: To evaluate the association between ondansetron exposure during pregnancy and risk of congenital malformati...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Huybrechts, Krista F., Hernandez-Diaz, Sonia, Straub, Loreen, Gray, Kathryn J., Zhu, Yanmin, Patorno, Elisabetta, Desai, Rishi J., Mogun, Helen, Bateman, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669077/
https://ncbi.nlm.nih.gov/pubmed/30561479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2018.18307
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