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Single-cell transcriptomics uncovers molecular funneling of cell identities during axolotl limb regeneration

Amputation of the axolotl forelimb results in the formation of a blastema, a transient tissue where progenitor cells accumulate prior to limb regeneration. Connective tissue (CT) – skeleton, periskeleton, tendon, dermis, interstitial fibroblasts – contributes the vast majority of cells that populate...

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Bibliografiske detaljer
Udgivet i:Science
Main Authors: Gerber, Tobias, Murawala, Prayag, Knapp, Dunja, Masselink, Wouter, Schuez, Maritta, Hermann, Sarah, Gac-Santel, Malgorzata, Nowoshilow, Sergej, Kagejama, Jorge, Khattak, Shahryar, Currie, Joshua, Camp, J. Gray, Tanaka, Elly M., Treutlein, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669047/
https://ncbi.nlm.nih.gov/pubmed/30262634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaq0681
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