Bi-layer blood vessel mimicking microfluidic platform for antitumor drug screening based on co-culturing 3D tumor spheroids and endothelial layers

Two-dimensional (2D) cell culture is not ideal for traditional drug screening, because 2D culture does not accurately mimic the physiological microenvironment of tumor cells. Thus, a drug-screening system which more closely mimics the microenvironment of in vivo tumors is necessary. Here, we present...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biomicrofluidics
Prif Awduron: Shi, Wentao, Reid, Lara, Huang, Yongyang, Uhl, Christopher G., He, Ran, Zhou, Chao, Liu, Yaling
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: AIP Publishing LLC 2019
Pynciau:
Regular Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669041/
https://ncbi.nlm.nih.gov/pubmed/31372195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5108681
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