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Assessing key decisions for transcriptomic data integration in biochemical networks

To gain insights into complex biological processes, genome-scale data (e.g., RNA-Seq) are often overlaid on biochemical networks. However, many networks do not have a one-to-one relationship between genes and network edges, due to the existence of isozymes and protein complexes. Therefore, decisions...

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Bibliografiset tiedot
Julkaisussa:PLoS Comput Biol
Päätekijät: Richelle, Anne, Joshi, Chintan, Lewis, Nathan E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668847/
https://ncbi.nlm.nih.gov/pubmed/31323017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007185
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