High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates

Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model of C. difficile was designed to evaluate the...

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Udgivet i:PLoS One
Main Authors: Tijerina-Rodríguez, Laura, Villarreal-Treviño, Licet, Baines, Simon D., Morfín-Otero, Rayo, Camacho-Ortíz, Adrián, Flores-Treviño, Samantha, Maldonado-Garza, Héctor, Rodríguez-Noriega, Eduardo, Garza-González, Elvira
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668830/
https://ncbi.nlm.nih.gov/pubmed/31365590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220671
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