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Defibrotide enhances fibrinolysis in human endotoxemia – a randomized, double blind, crossover trial in healthy volunteers

Defibrotide is approved for the treatment of sinusoidal obstruction syndrome after allogeneic stem cell transplantation. The exact mode of action of defibrotide is unclear and human in vivo data are scarce. In this randomized, double blind, crossover trial we included 20 healthy volunteers. Four wer...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Schoergenhofer, Christian, Buchtele, Nina, Gelbenegger, Georg, Derhaschnig, Ulla, Firbas, Christa, Kovacevic, Katarina D., Schwameis, Michael, Wohlfarth, Philipp, Rabitsch, Werner, Jilma, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668569/
https://ncbi.nlm.nih.gov/pubmed/31366975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47630-6
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