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Immunometabolic Dysfunction of Natural Killer Cells Mediated by the Hypoxia-CD73 Axis in Solid Tumors
NK cell infiltration into solid tumors is often low and is largely represented by the poorly-cytotoxic CD56(bright) subset. Numerous studies have demonstrated that CD73, overexpressed under conditions of hypoxia, is involved in a variety of physiological processes, while its overexpression has been...
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| Publicado no: | Front Mol Biosci |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6668567/ https://ncbi.nlm.nih.gov/pubmed/31396523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00060 |
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