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Quantifying Microsecond Exchange in Large Protein Complexes with Accelerated Relaxation Dispersion Experiments in the Solid State

Solid state NMR is a powerful method to obtain information on the structure and dynamics of protein complexes that, due to solubility and size limitations, cannot be achieved by other methods. Here, we present an approach that allows the quantification of microsecond conformational exchange in large...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Öster, Carl, Kosol, Simone, Lewandowski, Józef R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668460/
https://ncbi.nlm.nih.gov/pubmed/31366983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47507-8
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