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Quantifying Microsecond Exchange in Large Protein Complexes with Accelerated Relaxation Dispersion Experiments in the Solid State

Solid state NMR is a powerful method to obtain information on the structure and dynamics of protein complexes that, due to solubility and size limitations, cannot be achieved by other methods. Here, we present an approach that allows the quantification of microsecond conformational exchange in large...

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Publicado en:Sci Rep
Autores principales: Öster, Carl, Kosol, Simone, Lewandowski, Józef R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668460/
https://ncbi.nlm.nih.gov/pubmed/31366983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47507-8
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