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Sulfated polysaccharides interact with fibroblast growth factors and protect from denaturation

Fibroblast growth factors (FGFs) regulate embryonic development and homeostasis, including tissue and organ repair and specific aspects of metabolism. The basic FGF and acidic FGF, now known as FGF2 and FGF1, are widely used protein drugs for tissue repair. However, they are susceptible to denaturat...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Sun, Changye, Liu, Mengxin, Sun, Panwen, Yang, Mingming, Yates, Edwin A., Guo, Zhikun, Fernig, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668377/
https://ncbi.nlm.nih.gov/pubmed/31271519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12696
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