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Ablation of All Synaptobrevin vSNAREs Blocks Evoked But Not Spontaneous Neurotransmitter Release at Neuromuscular Synapses

Synaptic transmission occurs when an action potential triggers neurotransmitter release via the fusion of synaptic vesicles with the presynaptic membrane, driven by the formation of SNARE complexes composed of the vesicular (v)-SNARE synaptobrevin and the target (t)-SNAREs Snap-25 and syntaxin-1. Ne...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Liu, Yun, Sugiura, Yoshie, Südhof, Thomas C., Lin, Weichun
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668203/
https://ncbi.nlm.nih.gov/pubmed/31160536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0403-19.2019
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