The epigenome as a putative target for skin repair: the HDAC inhibitor Trichostatin A modulates myeloid progenitor plasticity and behavior and improves wound healing

BACKGROUND: The molecular pathways that drive bone marrow myeloid progenitors (BMMP) development are very well understood and include a tight controlled multi-stage gene hierarch. Monocytes are versatile cells that display remarkable plasticity and may give rise to specific subsets of macrophages to...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Cabanel, Mariana, da Costa, Thayse Pinheiro, EL-Cheikh, Marcia Cury, Carneiro, Katia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668089/
https://ncbi.nlm.nih.gov/pubmed/31366356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1998-9
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