The Anti-inflammatory Compound Candesartan Cilexetil Improves Neurological Outcomes in a Mouse Model of Neonatal Hypoxia

Recent studies suggest that mild hypoxia-induced neonatal seizures can trigger an acute neuroinflammatory response leading to long-lasting changes in brain excitability along with associated cognitive and behavioral deficits. The cellular elements and signaling pathways underlying neuroinflammation...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Quinlan, Sean, Merino-Serrais, Paula, Di Grande, Alessandra, Dussmann, Heiko, Prehn, Jochen H. M., Ní Chonghaile, Tríona, Henshall, David C., Jimenez-Mateos, Eva M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667988/
https://ncbi.nlm.nih.gov/pubmed/31396238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01752
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