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Sirt1 Overexpression Suppresses Fluoride-induced p53 Acetylation to Alleviate Fluoride Toxicity in Ameloblasts Responsible for Enamel Formation
Low-dose fluoride is an effective caries prophylactic, but high-dose fluoride is an environmental health hazard that causes skeletal and dental fluorosis. Treatments to prevent fluorosis and the molecular pathways responsive to fluoride exposure remain to be elucidated. Previously we showed that flu...
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| Publicat a: | Arch Toxicol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6667832/ https://ncbi.nlm.nih.gov/pubmed/29185024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-2135-2 |
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