5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication

In most mammalian cells, DNA replication occurs once, and only once between cell divisions. Replication initiation is a highly regulated process with redundant mechanisms that prevent errant initiation events. In lower eukaryotes, replication is initiated from a defined consensus sequence, whereas a...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Prikrylova, Terezia, Robertson, Julia, Ferrucci, Francesca, Konorska, Dorota, Aanes, Håvard, Manaf, Adeel, Zhang, Beibei, Vågbø, Cathrine Broberg, Kuśnierczyk, Anna, Gilljam, Karin M., Løvkvam-Køster, Caroline, Otterlei, Marit, Dahl, John Arne, Enserink, Jorrit, Klungland, Arne, Robertson, Adam B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667497/
https://ncbi.nlm.nih.gov/pubmed/31363131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47528-3
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