Germline Genetic Variants in GATA3 and Breast Cancer Treatment Outcomes in SWOG S8897 Trial and the Pathways Study

INTRODUCTION: GATA3 is a critical transcription factor in maintaining the differentiated state of luminal mammary epithelial cells. We sought to determine the prognostic and predictive roles of GATA3 genotypes for breast cancer. PATIENTS AND METHODS: Twelve single nucleotide polymorphisms (SNPs) wer...

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Publicado no:Clin Breast Cancer
Main Authors: Larsen, Victoria, Barlow, William E., Yang, Jun J., Zhu, Qianqian, Liu, Song, Kwan, Marilyn, Ergas, Isaac J., Roh, Janise M., Hutchins, Laura F., Kadlubar, Susan A, Albain, Kathy S., Rae, James M., Yeh, I-Tien, Ravdin, Peter M., Martino, Silvana, Lyss, Alan P., Osborne, C. Kent, Hortobagyi, Gabriel N., Kushi, Lawrence H., Hayes, Daniel F., Ambrosone, Christine B., Yao, Song
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667288/
https://ncbi.nlm.nih.gov/pubmed/30928413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clbc.2019.02.010
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