Germline Genetic Variants in GATA3 and Breast Cancer Treatment Outcomes in SWOG S8897 Trial and the Pathways Study

INTRODUCTION: GATA3 is a critical transcription factor in maintaining the differentiated state of luminal mammary epithelial cells. We sought to determine the prognostic and predictive roles of GATA3 genotypes for breast cancer. PATIENTS AND METHODS: Twelve single nucleotide polymorphisms (SNPs) wer...

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Udgivet i:Clin Breast Cancer
Main Authors: Larsen, Victoria, Barlow, William E., Yang, Jun J., Zhu, Qianqian, Liu, Song, Kwan, Marilyn, Ergas, Isaac J., Roh, Janise M., Hutchins, Laura F., Kadlubar, Susan A, Albain, Kathy S., Rae, James M., Yeh, I-Tien, Ravdin, Peter M., Martino, Silvana, Lyss, Alan P., Osborne, C. Kent, Hortobagyi, Gabriel N., Kushi, Lawrence H., Hayes, Daniel F., Ambrosone, Christine B., Yao, Song
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667288/
https://ncbi.nlm.nih.gov/pubmed/30928413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clbc.2019.02.010
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