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The Epigenetic State of PRDM16-regulated Enhancers in Radial Glia Controls Cortical Neuron Position

The epigenetic landscape is dynamically remodeled during neurogenesis. However, it is not understood how chromatin modifications in neural stem cells instruct the formation of complex structures in the brain. We report that the histone methyltransferase PRDM16 is required in radial glia to regulate...

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Dettagli Bibliografici
Pubblicato in:Neuron
Autori principali: Baizabal, José-Manuel, Mistry, Meeta, García, Miguel Turrero, Gómez, Nicolás, Olukoya, Olubusola, Tran, Diana, Johnson, Matthew B., Walsh, Christopher, Harwell, Corey
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667181/
https://ncbi.nlm.nih.gov/pubmed/29779941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.04.033
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