The Epigenetic State of PRDM16-regulated Enhancers in Radial Glia Controls Cortical Neuron Position

The epigenetic landscape is dynamically remodeled during neurogenesis. However, it is not understood how chromatin modifications in neural stem cells instruct the formation of complex structures in the brain. We report that the histone methyltransferase PRDM16 is required in radial glia to regulate...

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Veröffentlicht in:Neuron
Hauptverfasser: Baizabal, José-Manuel, Mistry, Meeta, García, Miguel Turrero, Gómez, Nicolás, Olukoya, Olubusola, Tran, Diana, Johnson, Matthew B., Walsh, Christopher, Harwell, Corey
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667181/
https://ncbi.nlm.nih.gov/pubmed/29779941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.04.033
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