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The Epigenetic State of PRDM16-regulated Enhancers in Radial Glia Controls Cortical Neuron Position

The epigenetic landscape is dynamically remodeled during neurogenesis. However, it is not understood how chromatin modifications in neural stem cells instruct the formation of complex structures in the brain. We report that the histone methyltransferase PRDM16 is required in radial glia to regulate...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Baizabal, José-Manuel, Mistry, Meeta, García, Miguel Turrero, Gómez, Nicolás, Olukoya, Olubusola, Tran, Diana, Johnson, Matthew B., Walsh, Christopher, Harwell, Corey
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667181/
https://ncbi.nlm.nih.gov/pubmed/29779941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.04.033
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