Loss of the Cholesterol-Binding Protein Prominin-1/CD133 Causes Disk Dysmorphogenesis and Photoreceptor Degeneration

Prominin-1/CD133 (Prom-1) is a commonly used marker of neuronal, vascular, hematopoietic and other stem cells, yet little is known about its biological role and importance in vivo. Here, we show that loss of Prom-1 results in progressive degeneration of mature photoreceptors with complete loss of vi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Zacchigna, Serena, Oh, Hideyasu, Wilsch-Bräuninger, Michaela, Missol-Kolka, Ewa, Jászai, József, Jansen, Sandra, Tanimoto, Naoyuki, Tonagel, Felix, Seeliger, Mathias, Huttner, Wieland B., Corbeil, Denis, Dewerchin, Mieke, Vinckier, Stefan, Moons, Lieve, Carmeliet, Peter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2009
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6666336/
https://ncbi.nlm.nih.gov/pubmed/19228982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2034-08.2009
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