Enhanced NMDA Receptor-Mediated Synaptic Transmission, Enhanced Long-Term Potentiation, and Impaired Learning and Memory in Mice Lacking IRSp53

IRSp53 is an adaptor protein that acts downstream of Rac and Cdc42 small GTPases and is implicated in the regulation of membrane deformation and actin filament assembly. In neurons, IRSp53 is an abundant postsynaptic protein and regulates actin-rich dendritic spines; however, its in vivo functions h...

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Publié dans:J Neurosci
Auteurs principaux: Kim, Myoung-Hwan, Choi, Jeonghoon, Yang, Jinhee, Chung, Woosuk, Kim, Ji-Hyun, Paik, Sang Kyoo, Kim, Karam, Han, Seungnam, Won, Hyejung, Bae, Young-Soo, Cho, Suk-Hee, Seo, Jinsoo, Bae, Yong Chul, Choi, Se-Young, Kim, Eunjoon
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2009
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6666077/
https://ncbi.nlm.nih.gov/pubmed/19193906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4306-08.2009
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