Opioids Depress Cortical Centers Responsible for the Volitional Control of Respiration

Respiratory depression limits provision of safe opioid analgesia and is the main cause of death in drug addicts. Although opioids are known to inhibit brainstem respiratory activity, their effects on cortical areas that mediate respiration are less well understood. Here, functional magnetic resonanc...

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Publicat a:J Neurosci
Autors principals: Pattinson, Kyle T. S., Governo, Ricardo J., MacIntosh, Bradley J., Russell, Elizabeth C., Corfield, Douglas R., Tracey, Irene, Wise, Richard G.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2009
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6666048/
https://ncbi.nlm.nih.gov/pubmed/19553457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1375-09.2009
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