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Tripartite Purinergic Modulation of Central Respiratory Networks during Perinatal Development: The Influence of ATP, Ectonucleotidases, and ATP Metabolites

ATP released during hypoxia from the ventrolateral medulla activates purinergic receptors (P2Rs) to attenuate the secondary hypoxic depression of breathing by a mechanism that likely involves a P2Y(1)R-mediated excitation of preBötzinger complex (preBötC) inspiratory rhythm-generating networks. In t...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Huxtable, Adrianne G., Zwicker, Jennifer D., Poon, Betty Y., Pagliardini, Silvia, Vrouwe, Sebastian Q., Greer, John J., Funk, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6666021/
https://ncbi.nlm.nih.gov/pubmed/19940166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2660-09.2009
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