Brain-Derived Neurotrophic Factor Controls Activity-Dependent Maturation of CA1 Synapses by Downregulating Tonic Activationof Presynaptic Kainate Receptors

Immature hippocampal synapses express presynaptic kainate receptors (KARs), which tonically inhibit glutamate release. Presynaptic maturation involves activity-dependent downregulation of the tonic KAR activity and consequent increase in release probability; however, the molecular mechanisms underly...

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Publicado no:J Neurosci
Main Authors: Sallert, Marko, Rantamäki, Tomi, Vesikansa, Aino, Anthoni, Heidi, Harju, Kirsi, Yli-Kauhaluoma, Jari, Taira, Tomi, Castren, Eero, Lauri, Sari E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665927/
https://ncbi.nlm.nih.gov/pubmed/19741136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0560-09.2009
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