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Synaptic Activity-Mediated Suppression of p53 and Induction of Nuclear Calcium-Regulated Neuroprotective Genes Promote Survival through Inhibition of Mitochondrial Permeability Transition

Cellular stress caused by genetic or environmental factors are considered to be the major inducers of cell death under pathological conditions. Induction of the apoptotic function of the tumor suppressor p53 is a common cellular response to severe genotoxic and oxidative stresses. In the nervous sys...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Lau, David, Bading, Hilmar
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665744/
https://ncbi.nlm.nih.gov/pubmed/19357269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0802-09.2009
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