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Multidrug Cancer Therapy in Metastatic Castrate-Resistant Prostate Cancer: An Evolution-Based Strategy

PURPOSE: Integration of evolutionary dynamics into systemic therapy for metastatic cancers can prolong tumor control compared with standard maximum tolerated dose (MTD) strategies. Prior investigations have focused on monotherapy, but many clinical cancer treatments combine two or more drugs. Optimi...

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發表在:Clin Cancer Res
Main Authors: West, Jeffrey B., Dinh, Mina N., Brown, Joel S., Zhang, Jingsong, Anderson, Alexander R., Gatenby, Robert A.
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665681/
https://ncbi.nlm.nih.gov/pubmed/30992299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0006
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