Dopamine Release in Dissociable Striatal Subregions Predicts the Different Effects of Oral Methylphenidate on Reversal Learning and Spatial Working Memory

Previous data suggest that methylphenidate can have variable effects on different cognitive tasks both within and between individuals. This is thought to be underpinned by inverted U-shaped relationships between cognitive performance and dopaminergic activity in relatively separate fronto-striatal c...

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Publicado en:J Neurosci
Main Authors: Clatworthy, Philip L., Lewis, Simon J. G., Brichard, Laurent, Hong, Young T., Izquierdo, David, Clark, Luke, Cools, Roshan, Aigbirhio, Franklin I., Baron, Jean-Claude, Fryer, Timothy D., Robbins, Trevor W.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665353/
https://ncbi.nlm.nih.gov/pubmed/19369539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3266-08.2009
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