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Phosphatidylinositol 4,5-Bisphosphate-Dependent Interaction of Myelin Basic Protein with the Plasma Membrane in Oligodendroglial Cells and Its Rapid Perturbation by Elevated Calcium

Myelin basic protein (MBP) is an essential structural component of CNS myelin. The electrostatic association of this positively charged protein with myelin-forming membranes is a crucial step in myelination, but the mechanism that regulates myelin membrane targeting is not known. Here, we demonstrat...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Nawaz, Schanila, Kippert, Angelika, Saab, Aiman S., Werner, Hauke B., Lang, Thorsten, Nave, Klaus-Armin, Simons, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665343/
https://ncbi.nlm.nih.gov/pubmed/19369548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3955-08.2009
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