Direct Control of Peripheral Lipid Deposition by CNS GLP-1 Receptor Signaling Is Mediated by the Sympathetic Nervous System and Blunted in Diet-Induced Obesity

We investigated a possible role of the central glucagon-like peptide (GLP-1) receptor system as an essential brain circuit regulating adiposity through effects on nutrient partitioning and lipid metabolism independent from feeding behavior. Both lean and diet-induced obesity mice were used for our e...

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Publicado no:J Neurosci
Main Authors: Nogueiras, Ruben, Pérez-Tilve, Diego, Veyrat-Durebex, Christelle, Morgan, Donald A., Varela, Luis, Haynes, William G., Patterson, James T., Disse, Emmanuel, Pfluger, Paul T., López, Miguel, Woods, Stephen C., DiMarchi, Richard, Diéguez, Carlos, Rahmouni, Kamal, Rohner-Jeanrenaud, Françoise, Tschöp, Matthias H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665241/
https://ncbi.nlm.nih.gov/pubmed/19420258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5977-08.2009
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