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Abnormal Network Activity in a Targeted Genetic Model of Human Double Cortex

In human patients, cortical dysplasia produced by Doublecortin (DCX) mutations lead to mental retardation and intractable infantile epilepsies, but the underlying mechanisms are not known. DCX(−/−) mice have been generated to investigate this issue. However, they display no neocortical abnormality,...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Ackman, James B., Aniksztejn, Laurent, Crépel, Valérie, Becq, Hélène, Pellegrino, Christophe, Cardoso, Carlos, Ben-Ari, Yehezkel, Represa, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664957/
https://ncbi.nlm.nih.gov/pubmed/19144832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4093-08.2009
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