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Relationship of B7-H3 expression in tumor cells and tumor vasculature with FOXP3+ regulatory T cells in renal cell carcinoma

BACKGROUND: B7-H3 (CD276), an immune checkpoint molecule, regulates the tumor-immune microenvironment and controls the aggressiveness of various tumors. Although B7-H3 expression has been associated with the number of tumor-infiltrating FOXP3+ regulatory T cells, little information is available abou...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Manag Res
Hauptverfasser: Inamura, Kentaro, Amori, Gulanbar, Yuasa, Takeshi, Yamamoto, Shinya, Yonese, Junji, Ishikawa, Yuichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664858/
https://ncbi.nlm.nih.gov/pubmed/31440091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S209205
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