A Human Organotypic Microfluidic Tumor Model Permits Investigation Of The Interplay Between Patient-Derived Fibroblasts And Breast Cancer Cells

Tumor-stroma interactions significantly influence cancer cell metastasis and disease progression. These interactions partly comprise crosstalk between tumor and stromal fibroblasts, but the key molecular mechanisms within the crosstalk that govern cancer invasion are still unclear. Here we adapted o...

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Pubblicato in:Cancer Res
Autori principali: Truong, Danh D., Kratz, Alexander, Park, Jin G., Barrientos, Eric S., Saini, Harpinder, Nguyen, Toan, Pockaj, Barbara, Mouneimne, Ghassan, LaBaer, Joshua, Nikkhah, Mehdi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664809/
https://ncbi.nlm.nih.gov/pubmed/30992322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2293
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