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Estimation of a significance threshold for genome-wide association studies

BACKGROUND: Selection of an appropriate statistical significance threshold in genome-wide association studies is critical to differentiate true positives from false positives and false negatives. Different multiple testing comparison methods have been developed to determine the significance threshol...

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Publicat a:BMC Genomics
Autors principals: Kaler, Avjinder S., Purcell, Larry C.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664749/
https://ncbi.nlm.nih.gov/pubmed/31357925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5992-7
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