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Novel Insight Into the Etiology of Autism Spectrum Disorder Gained by Integrating Expression Data With Genome-wide Association Statistics

BACKGROUND: A recent genome-wide association study (GWAS) of autism spectrum disorder (ASD) (n(cases) = 18,381, n(controls) = 27,969) has provided novel opportunities for investigating the etiology of ASD. Here, we integrate the ASD GWAS summary statistics with summary-level gene expression data to...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Pain, Oliver, Pocklington, Andrew J., Holmans, Peter A., Bray, Nicholas J., O’Brien, Heath E., Hall, Lynsey S., Pardiñas, Antonio F., O’Donovan, Michael C., Owen, Michael J., Anney, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664597/
https://ncbi.nlm.nih.gov/pubmed/31230729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2019.04.034
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