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The growth inhibitory effect of human gingiva-derived mesenchymal stromal cells expressing interferon-β on tongue squamous cell carcinoma cells and xenograft model

BACKGROUND: Interferon-β (IFN-β) is a cytokine with pleiotropic cellular functions, including antiviral, antiproliferative, and immunomodulatory activities. IFN-β inhibits multiple tumor cell growth in vitro. However, the contradiction between the therapeutic dose of IFN-β and its maximally tolerate...

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Publicat a:Stem Cell Res Ther
Autors principals: Du, Lingqian, Liang, Qianyu, Ge, Shaohua, Yang, Chengzhe, Yang, Pishan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664557/
https://ncbi.nlm.nih.gov/pubmed/31358054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1320-z
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