Metabolites of the Nitric Oxide (NO) Pathway Are Altered and Indicative of Reduced NO and Arginine Bioavailability in Patients with Cardiometabolic Diseases Complicated with Chronic Wounds of Lower Extremities: Targeted Metabolomics Approach (LC-MS/MS)

OBJECTIVE: The status of metabolites of the nitric oxide (NO) pathway in patients with chronic wounds in the course of cardiometabolic diseases is largely unknown. Yet arginine supplementation and citrulline supplementation as novel therapeutic modalities aimed at increasing NO are tested. MATERIAL...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Krzystek-Korpacka, Małgorzata, Wiśniewski, Jerzy, Fleszar, Mariusz G., Bednarz-Misa, Iwona, Bronowicka-Szydełko, Agnieszka, Gacka, Małgorzata, Masłowski, Leszek, Kędzior, Krzysztof, Witkiewicz, Wojciech, Gamian, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664544/
https://ncbi.nlm.nih.gov/pubmed/31396302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5965721
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