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Exosomes derived from mesenchymal stem cells reverse EMT via TGF-β1/Smad pathway and promote repair of damaged endometrium

BACKGROUND: Intrauterine adhesion (IUA) is one of the most serious complications in patients with endometrial repair disorder after injury. Currently, there is no effective treatment for IUA. Stem cell is the main candidate of new therapy, which functions mainly through paracrine mechanism. Stem-der...

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Pubblicato in:Stem Cell Res Ther
Autori principali: Yao, Yuan, Chen, Ran, Wang, Guowu, Zhang, Yu, Liu, Fang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664513/
https://ncbi.nlm.nih.gov/pubmed/31358049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1332-8
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