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Conserved Glu-47 and Lys-50 residues are critical for UDP-N-acetylglucosamine/UMP antiport activity of the mouse Golgi-associated transporter Slc35a3

Nucleotide sugar transporters (NSTs) regulate the flux of activated sugars from the cytosol into the lumen of the Golgi apparatus where glycosyltransferases use them for the modification of proteins, lipids, and proteoglycans. It has been well-established that NSTs are antiporters that exchange nucl...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Toscanini, M. Agustina, Favarolo, M. Belén, Gonzalez Flecha, F. Luis, Ebert, Berit, Rautengarten, Carsten, Bredeston, Luis M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664187/
https://ncbi.nlm.nih.gov/pubmed/31118275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008827
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