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Toll family members bind multiple Spätzle proteins and activate antimicrobial peptide gene expression in Drosophila
The Toll signaling pathway in Drosophila melanogaster regulates several immune-related functions, including the expression of antimicrobial peptide (AMP) genes. The canonical Toll receptor (Toll-1) is activated by the cytokine Spätzle (Spz-1), but Drosophila encodes eight other Toll genes and five o...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6664172/ https://ncbi.nlm.nih.gov/pubmed/31088910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006804 |
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